An electron micrograph of an influenza virus, showing details of its structure.
Credit: Cynthia Goldsmith/CDC
Viruses
Viruses are tiny, ranging in size from about 20 to 400 nanometers in diameter. Billions can fit on the head of a pin. Some are rod shaped; others are round and 20 sided; and yet others have fanciful forms, with multisided “heads” and cylindrical “tails.”
Viruses are responsible for a wide range of diseases, including the common cold, measles, chicken pox, genital herpes, and influenza.
Viruses are simply packets of nucleic acid, either DNA or RNA, surrounded by a protein shell and sometimes fatty materials called lipids. Outside a living cell, a virus is a dormant particle, lacking the raw materials for reproduction. Only when it enters a host cell does it go into action, hijacking the cell’s metabolic machinery to produce copies of itself that may burst out of infected cells or simply bud off a cell membrane. This lack of self-sufficiency means that viruses cannot be grown in artificial media for scientific research or vaccine development; they can be grown only in living cells, fertilized eggs, tissue cultures, or bacteria.