The National Academies

The National Academies: What You Need To Know About Infectious Disease

What You Need To Know About Infectious Disease

Facing the Reality of Drug-Resistant Tuberculosis in India: Challenges and Potential Solutions: Summary of a Joint Workshop (2012)

An estimated 8.8 million people fell ill with tuberculosis (TB) in 2010 and 1.4 million died from the disease. Although antibiotics to treat TB were developed in the 1950s and are effective against a majority of TB cases, resistance to these antibiotics has emerged over the years, resulting in the growing spread of multidrug-resistant (MDR) TB. Due to challenges in timely and accurate diagnosis of drug-resistant TB, length and tolerability of treatment regimens, and expense of second-line anti-TB drugs, effectively controlling the disease requires complex public health interventions.

The IOM Forum on Drug Discovery, Development, and Translation held three international workshops to gather information from local experts around the world on the threat of drug resistant TB and how the challenges it presents can be met. Workshops were held in South Africa and Russia in 2010. The third workshop was held April 18-19, 2011, in New Delhi, India, in collaboration with the Indian National Science Academy and the Indian Council of Medical Research. The aim of the workshop was to highlight key challenges to controlling the spread of drug-resistant strains of TB in India and to discuss strategies for advancing and integrating local and international efforts to prevent and treat drug-resistant TB. This document summarizes the workshop.

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What do you know about infectious disease?

True or False: Antibiotics work by introducing an agent that resembles a disease-causing microbe, thus stimulating the body's immune system to recognize it as foreign, destroy it, and "remember" it, so that it can more easily identify and destroy any similar, disease-causing microbes that it later encounters.

  • Sorry, that’s incorrect.

    The above describes how vaccines work. Antibiotics work by either killing bacteria or stopping them from reproducing, allowing the body's natural defenses to eliminate the pathogens.

  • Correct!

    The above describes how vaccines work. Antibiotics work by either killing bacteria or stopping them from reproducing, allowing the body's natural defenses to eliminate the pathogens.